TCM categorizes disease causes into three main groups: external pathogens that invade from the environment, internal emotions that damage organs directly, and lifestyle factors that deplete the body over time. Each group has specific patterns and signatures — which is why TCM practitioners ask about your emotional life and daily habits, not just your symptoms.

The Six Exogenous Pathogens 六淫

Wind, Cold, Summer Heat, Dampness, Dryness, and Fire are the six climatic forces that, in excess or at the wrong time, become disease-causing pathogens. In normal amounts, they're just weather. As pathogens (邪氣), they invade through the skin and pores, mucous membranes, or mouth and nose — triggering exterior patterns first, then penetrating deeper if the body's defensive Qi (Wei Qi) can't repel them.

Wind風邪
Season: Spring · Combines with everything
"The leader of all diseases" (百病之長). Wind is Yang in nature, opens pores, and allows other pathogens in. It moves rapidly and changes constantly — making symptoms wandering and unpredictable.
→ Wandering joint pain (moves from joint to joint) → Sudden onset, rapid change → Itching, tremors, convulsions → Aversion to wind, fever, spontaneous sweating
Cold寒邪
Season: Winter · Injures Yang
Cold is Yin in nature. It contracts and congeals — blood vessels, muscles, channels. Pain from Cold is sharp, severe, and improves with warmth. Cold damages Spleen and Kidney Yang most.
→ Severe, cramping, stabbing pain → Aversion to cold, no sweating → White or pale complexion, pale tongue → Tight (緊) pulse
Summer Heat暑邪
Season: Summer only · Always accompanied by Dampness
Summer Heat is exclusively a summer pathogen. It is Yang and upward-moving, consumes Qi and damages fluids rapidly. Almost always paired with Dampness in summer months.
→ High fever, heavy sweating, thirst → Mental restlessness, sudden collapse (heat stroke) → Scanty dark urine → With Dampness: heavy head, nausea, chest oppression
Dampness濕邪
Season: Late summer (長夏) · Hardest to clear
Dampness is heavy, turbid, and sticky — the most stubborn of all pathogens. It tends downward (lower body symptoms), obstructs Qi flow, and most injures the Spleen (which fears Dampness). Symptoms are chronic, recurrent, and slow to resolve.
→ Body heaviness and fatigue → Sticky or greasy tongue coat → Cloudy or turbid secretions → Digestive symptoms: nausea, loose stool, poor appetite
Dryness燥邪
Season: Autumn · Injures Lung and fluids
Dryness consumes body fluids and particularly targets the Lung (the most moisture-sensitive organ). Autumn Dryness comes in two types: warm-dry (初秋) and cool-dry (深秋).
→ Dry cough with little or no phlegm → Dry nose, lips, throat, skin → Constipation (dry stools) → Fever with little or no sweating
Fire / Heat火邪 / 熱邪
Season: Summer · Also transforms from any pathogen
Fire is intense Yang heat that rises upward, blazes outward, and most injures Heart and Liver. Any of the other five pathogens can transform into Fire when they penetrate deeply and linger.
→ High fever, intense thirst, agitation → Red face, eyes, and tongue; rapid pulse → Bleeding: vomiting blood, nosebleeds, skin eruptions → Mental disturbances: mania, delirium

The Seven Emotions 七情

Internal causes of disease in TCM are primarily the seven emotions. Unlike external pathogens that invade the body from outside, emotions damage organs directly from within — specifically by disrupting the upward/downward/inward/outward flow of Qi. The damage happens not from feeling these emotions occasionally, but from their extreme intensity or prolonged duration.

EmotionOrgan DamagedQi MovementClinical Patterns
Joy喜 · Xǐ Heart 心 Qi slackens (氣緩) Excessive excitement → scattered attention, palpitations, hypomania, mental instability
Anger怒 · Nù Liver 肝 Qi rises (氣上) Flushed face, red eyes, headache, hematemesis — in severe cases, fainting from Qi surging upward
Pensiveness / Worry思 · Sī Spleen 脾 Qi knots (氣結) Overthinking stagnates Spleen Qi: poor appetite, bloating, weak digestion, forgetfulness
Grief / Sadness悲/憂 · Bēi/Yōu Lung 肺 Qi dissolves (氣消) Chronic sadness depletes Lung Qi: shortness of breath, fatigue, lowered immunity, crying without cause
Fear恐 · Kǒng Kidney 腎 Qi descends (氣下) Chronic fear depletes Kidney Qi: urinary incontinence, low back weakness, sexual dysfunction
Fright / Shock驚 · Jīng Heart & Kidney Qi scatters (氣亂) Sudden shock scatters Qi and disturbs Shen: palpitations, insomnia, anxiety, startling easily

The five-to-seven-emotion distinction matters: the foundational five (joy, anger, pensiveness, grief, fear) each map to one of the Five Zang. Fright (驚) is sometimes listed separately from fear because it's acute-onset while fear is chronic. Both primarily affect the Heart and Kidney.

Lifestyle Factors

Beyond environment and emotions, TCM recognizes a category of causes that are purely about how you live — dietary patterns, physical exertion, sexual activity, and rest. These don't cause dramatic acute diseases, but they silently deplete the body over years.

Diet 飲食
Irregular eating depletes Qi and Blood. Overeating overwhelms Stomach (food stagnation). Undereating starves Qi generation. Cold/raw foods injure Spleen Yang. The wrong flavors in excess damage their organ: too sour injures Liver, too sweet injures Spleen, too spicy injures Lung.
Physical Overexertion 勞倦
Excess physical labor depletes Spleen Qi. Prolonged sitting stagnates Qi and Blood, harms the Spleen. Prolonged standing injures the Kidneys and bones. Excessive eye use (screens) depletes Liver Blood.
Mental Overwork 勞神
Prolonged intense thinking, studying, or worry depletes Heart Blood and Spleen Qi simultaneously. This is extremely common in modern life — symptoms include forgetting easily, poor concentration, fatigue after thinking, and vivid dreams.
Sexual Activity 房勞
Excessive sexual activity, especially in men (loss of Jing), depletes Kidney Essence. Symptoms: low back pain, tinnitus, night sweats, diminished libido, premature aging. TCM is not moralistic about this — it's purely about conservation of a finite resource.
Secondary Causes · 繼發病因

Phlegm and Blood Stasis

These are not primary causes but derived pathogens — formed when primary causes remain unresolved. Once formed, they become powerful causes of disease themselves.

Phlegm 痰飲 (Tán Yǐn)
Phlegm forms when Lung, Spleen, or Kidney dysfunction fails to metabolize Body Fluids properly — fluids congeal into thick, pathological Phlegm. "Phlegm is the source of a hundred diseases" (痰為百病之源). It can lodge anywhere: Phlegm misting the Heart → mental confusion; Phlegm in the channels → numbness; Phlegm-Fire → mania; Phlegm in the throat → globus sensation (梅核氣).
Blood Stasis 血瘀 (Xuè Yū)
Blood Stasis forms when Qi deficiency fails to move Blood, Qi stagnation stops Blood flow, Cold congeals Blood, or Heat thickens Blood. It causes fixed, stabbing pain (worse at night), masses, dark purple tongue with petechiae, and choppy pulse. Virtually every chronic disease eventually involves some element of Blood Stasis, which is why Blood-activating herbs appear in so many formulas.

"Wind is the leader of all diseases — it opens the way for every other pathogen to enter."

風為百病之長 — Classical TCM Principle

Reading Disease Causes in Daily Life

TCM's etiology framework turns everyday observations into clinical clues. Waking at 3 AM every night? The Liver time (1–3 AM) is disturbed — look for Liver Qi stagnation or Blood deficiency. Catching every cold that circulates? Wei Qi deficiency, often from Lung weakness. Chronic migraines that worsen with stress? Liver Qi rising — the anger pathogen even when no anger is felt.

The emotion-organ connections are particularly useful for understanding psychosomatic patterns. The Spleen's link to pensiveness explains why academic overload reliably causes digestive issues. The Lung's link to grief explains the breathlessness and immunity drops during bereavement. These aren't metaphors — TCM treats them as literal physiological mechanisms.

Understanding disease causes doesn't mean living in fear of weather or emotions. It means reading your symptoms in context — seeing the pattern behind the complaint, and addressing root causes rather than just suppressing signs.